Silent myocardial ischemia during holter monitoring in ischemic heart disease.

Reliability of Holter registration in ischemic heart disease

Introduction We studied the reliability of a new ST-segment analysis on a 24-hour 12-lead holter recording comparing ST-depression during exercise testing with active molsidomine and placebo drugs in a randomized, double-blind, crossover, clinical trial. Methods and results 35 patients with proven coronary heart disease received either 4 mg regular molsidomine, 8 mg molsidomine SR (Sustained Re...

Silent myocardial ischemia.

Silent myocardial ischemia is increasingly recognized as a common phenomenon in a variety of people with coronary artery disease. The natural history is poorly understood, but available data suggest that silent ischemia adversely affects prognosis in all groups studied. Based on this information, we believe that efforts should be directed at detecting and aggressively treating silent ischemic e...

Silent myocardial ischemia during ambulatory electrocardiographic monitoring in patients with effort angina.

The frequency and characteristics of asymptomatic ischemic attacks were investigated in 39 patients with effort angina. During 24 hour Holter monitoring, 32 of the 39 patients displayed one or more episodes of ischemic ST depression. Eight patients had attacks (n = 25) always accompanied by pain; 9 patients had only asymptomatic ischemic episodes (n = 40) and 15 patients had both symptomatic (n...

Silent small-vessel cerebrovascular disease and silent myocardial ischemia in families with premature coronary disease.

CAD ! 60 years of age. Siblings with known clinical vascular disease and diabetes were excluded. The siblings underwent brain magnetic resonance imaging to identify WMH using the published criteria of the ARIC study [5] , and a maximal exercise test with thallium-201 single-photon emission tomography of the heart with rest and reperfusion imaging. Exercise-induced ischemia was defined as a reve...

Myocardial perfusion reserve in ischemic heart disease.